Volume 6, Issue 4, December 2020, Page: 68-70
Study on Antiviral Activities of Glycyrrhizin
Changchao Huan, Institutes of Agricultural Science and Technology Development, College of Veterinary Medicine, Yangzhou University, Yangzhou, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China; Key Laboratory of Avian Bioproduct Development, Ministry of Agriculture and Rural Affairs, Yangzhou, China
Chunqin Chen, Institutes of Agricultural Science and Technology Development, College of Veterinary Medicine, Yangzhou University, Yangzhou, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China; Key Laboratory of Avian Bioproduct Development, Ministry of Agriculture and Rural Affairs, Yangzhou, China
Weiyin Xu, Institutes of Agricultural Science and Technology Development, College of Veterinary Medicine, Yangzhou University, Yangzhou, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China; Key Laboratory of Avian Bioproduct Development, Ministry of Agriculture and Rural Affairs, Yangzhou, China
Tingting Guo, College of Medicine, Yangzhou University, Yangzhou, China
Haochun Pan, Institutes of Agricultural Science and Technology Development, College of Veterinary Medicine, Yangzhou University, Yangzhou, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China; Key Laboratory of Avian Bioproduct Development, Ministry of Agriculture and Rural Affairs, Yangzhou, China
Song Gao, Institutes of Agricultural Science and Technology Development, College of Veterinary Medicine, Yangzhou University, Yangzhou, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China; Key Laboratory of Avian Bioproduct Development, Ministry of Agriculture and Rural Affairs, Yangzhou, China
Received: Oct. 16, 2020;       Accepted: Nov. 2, 2020;       Published: Nov. 9, 2020
DOI: 10.11648/j.ijbecs.20200604.11      View  30      Downloads  18
Abstract
Licorice has been a common Chinese medicine for thousands of years, which has good medicinal value and nutritional value. Is widely apply to traditional Chinese medicine. Many studies have shown that licorice contains more than 20 triterpenoids and nearly 300 flavonoids. According to the literature, licorice has many activities such as antibacterial, antiviral, antioxidant, and anticancer. It not only directly inactivates the virus, but also inhibits its adsorption. However, glycyrrhizin, glycyrrhetinic acid, glycyrrhiza polysaccharide and glycyrrhiza flavonoids are the main components of licorice which possess antiviral and antimicrobial activities. Among them, glycyrrhizin has many pharmacological activities, such as antiviral, anti-inflammatory, anti-tumor, antibacterial and many other activities. This paper provides a summary of antiviral activities of glycyrrhizin. This active ingredients and possible mechanisms are summarized in detail. The results showed that glycyrrhizin was widely used in antiviral field, but its material basis and mechanism of action were not perfect and unified. A large number of literatures about glycyrrhizin anti-virus were reviewed and analyzed, and it was suggested that more different ways should be adopted to study it, so as to provide a broader theoretical basis for developing new antivirus drugs of glycyrrhizin. It is hoped that this review will be helpful to further study the potential therapeutic effect of glycyrrhizin as an antiviral drug.
Keywords
Glycyrrhizin, Antiviral, Chinese Medicine
To cite this article
Changchao Huan, Chunqin Chen, Weiyin Xu, Tingting Guo, Haochun Pan, Song Gao, Study on Antiviral Activities of Glycyrrhizin, International Journal of Biomedical Engineering and Clinical Science. Vol. 6, No. 4, 2020, pp. 68-70. doi: 10.11648/j.ijbecs.20200604.11
Copyright
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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