Volume 5, Issue 3, September 2019, Page: 31-39
Phytochemical Analysis and Assessment of Antibacterial and Antioxidant Activities of Phytolacca dodecandra L. Herit Leaf Extracts (Phytolaccaceae)
Jeff Bekomo Iteku, Higher Pedagogical Institute of Yakoma, Nord-Ubangi City, Democratic Republic of the Congo; Department of Biology, Faculty of Science, University of Kinshasa, Kinshasa City, Democratic Republic of the Congo
Ornella Mbayi, Department of Biology, Faculty of Science, University of Kinshasa, Kinshasa City, Democratic Republic of the Congo
Gedeon Ngiala Bongo, Department of Biology, Faculty of Science, University of Kinshasa, Kinshasa City, Democratic Republic of the Congo
Paulin Kapepula Mutwale, Faculty of Pharmaceutical Sciences, University of Kinshasa, Kinshasa City, Democratic Republic of the Congo
Jose Mulwahali Wambale, Faculty of Pharmaceutical Sciences, University of Kinshasa, Kinshasa City, Democratic Republic of the Congo
Emmanuel Lengbiye, Department of Biology, Faculty of Science, University of Kinshasa, Kinshasa City, Democratic Republic of the Congo
Clement Liyongo Inkoto, Department of Biology, Faculty of Science, University of Kinshasa, Kinshasa City, Democratic Republic of the Congo
Samy Ngunde Ngunde, Higher Pedagogical Institute of Yakoma, Nord-Ubangi City, Democratic Republic of the Congo
Koto-te-Nyiwa Ngbolua, Department of Biology, Faculty of Science, University of Kinshasa, Kinshasa City, Democratic Republic of the Congo; Department of Environmental Sciences, University of Gbadolite, Nord-Ubangi City, Democratic Republic of the Congo
Received: Aug. 23, 2019;       Accepted: Sep. 26, 2019;       Published: Oct. 11, 2019
DOI: 10.11648/j.ijbecs.20190503.11      View  46      Downloads  12
Abstract
From times immemorial, medicinal plants have been used to relieve and cure human diseases. Currently, the control of bacterial infections is becoming complex due to the concern of antibiotic resistance, which has been a significant global health problem. The aim of this work was to determine the phytochemical composition as well as to assess the bioactivities of Phytolacca dodecandra leaf extracts. The leaves of P. dodecandra were collected in January 2017 at Yakoma city, Nord-Ubangi, DRC. Three bacterial strains namely Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 8739 and Pseudomonas aeroginosa ATCC 9027 were used for the assessment of the antibacterial activity. The qualitative and quantitative phytochemical screening were used for compound identification. The antioxidant activity was assessed using ABTS and DPPH scavenging tests while the antibacterial activity was performed using the diffusion method. The findings show that leaves of this plant are rich in flavonoids, anthocyanins, terpenoids and irrioids. The inhibitory concentration 50 (IC50) values obtained in the ATBS test are lower than those of the DPPH test. The antibacterial activity of this plant was low against the three strains used. These in vitro findings show that medicinal plants have very important biological properties that have many applications in various fields such as medicine, pharmacy and agriculture.
Keywords
Phytolacca dodecandra, Antibiotic Resistance, Bioactivity, Yakoma, DRC
To cite this article
Jeff Bekomo Iteku, Ornella Mbayi, Gedeon Ngiala Bongo, Paulin Kapepula Mutwale, Jose Mulwahali Wambale, Emmanuel Lengbiye, Clement Liyongo Inkoto, Samy Ngunde Ngunde, Koto-te-Nyiwa Ngbolua, Phytochemical Analysis and Assessment of Antibacterial and Antioxidant Activities of Phytolacca dodecandra L. Herit Leaf Extracts (Phytolaccaceae), International Journal of Biomedical Engineering and Clinical Science. Vol. 5, No. 3, 2019, pp. 31-39. doi: 10.11648/j.ijbecs.20190503.11
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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